Knicks vs Pistons Game 2 Prediction, NBA 24-25 Playoffs: Odds, Spread, Moneyline, Best Bets

New York Knicks vs. Detroit Pistons Game 2 Prediction, NBA 2025 Playoffs: The New York Knicks aim to build on their Game 1 comeback victory as they host the Detroit Pistons in Game 2 of their Eastern Conference First Round series on Monday, April 21, 2025, at 7:30 p.m. ET.

The Knicks overcame a nine-point deficit in Game 1 with a remarkable 21-0 run in the fourth quarter, securing a 123-112 win. Jalen Brunson led the Knicks with 34 points, while Karl-Anthony Towns contributed 23 points and 11 rebounds.

Cameron Payne added 14 points off the bench, 11 of which came in the decisive fourth quarter. The Pistons, despite a strong performance from Tobias Harris (25 points) and Cade Cunningham (21 points, 12 assists), struggled in the final period. Cunningham, who had averaged over 30 points against the Knicks in the regular season, was limited to 8-for-21 shooting in Game 1.

Knicks vs Pistons Game Information & How to Watch

Matchup: New York Knicks (3) vs Detroit Pistons (6)

Date & Time: Monday, April 21, 2025, at 7:30 p.m. ET

Location: Madison Square Garden, New York, NY

TV: TNT, MSG

Knicks vs. Pistons Betting Odds

Point Spread: Knicks -6.5

Moneyline: Knicks -273 | Pistons +221

Over/Under: 220.5

Knicks vs. Pistons Team Insights

New York Knicks

The Knicks showcased resilience in Game 1, with Brunson's leadership and scoring prowess at the forefront. Towns' inside presence and Payne's bench scoring were pivotal. However, concerns remain regarding the consistency of bench players like Deuce McBride and Landry Shamet.

Detroit Pistons

The Pistons demonstrated their potential with strong performances from Harris and Cunningham. Yet, their inexperience was evident in the fourth quarter collapse. The status of Isaiah Stewart, who suffered a knee injury in Game 1, is uncertain and could impact their frontcourt depth.

Knicks vs Pistons Head-to-Head Matchups (2024-25 Regular Season)

• Apr 10, 2025: Pistons 115, Knicks 106
• Jan 13, 2025: Pistons 124, Knicks 119
• Dec 7, 2024: Pistons 120, Knicks 111
• Nov 1, 2024: Knicks 128, Pistons 98

The Pistons won the regular-season series 3-1, including victories in the last three matchups.

Knicks vs. Pistons Injury Report

New York Knicks

No significant injuries reported.

Detroit Pistons

Isaiah Stewart (knee): Questionable

Knicks vs. Pistons Betting Insights

• Against the Spread (ATS): Knicks are 5-5 in their last 10 games; Pistons are 6-4.
• Over/Under Trends: The total has gone over in 60% of Knicks' games and 49% of Pistons' games this season.
• Home/Away Records: Knicks have a 28-13 home record; Pistons are 19-22 on the road.

Knicks vs. Pistons Expert Prediction

• ATS Pick: Pistons (+6.5)
• Over/Under Pick: Over (220.5)
• Score Prediction: Knicks 115 - Pistons 110

While the Knicks are favored to win, the Pistons' recent success against New York and their strong performances suggest they could cover the spread. The total points are expected to go over 220.5, considering both teams' scoring capabilities.

Knicks vs. Pistons Best Bets

• Pistons +6.5: Given Detroit's recent performances against New York, they have a good chance to keep the game within the spread.
• Over 220.5 Total Points: Both teams have trends favoring the over, making this a viable bet.

Disclaimer: Betting should be done responsibly and only where legal. Always adhere to local laws, regulations, and guidelines. This article provides information for entertainment purposes and does not encourage gambling.